Pharma Tips-7

56. Dopamine acts on dopamine receptors in renal vasculature, causing vasodilation, increasing GFR, and increasing renal blood flow (RBF), and sodium excretion.
57. Dobutamine has beta1>beta2 increases HR, used in CHF and causes tachyphylaxis.
58. NE acts on alpha 1 & 2, beta 1, and has no beta 2 actions, increases HR, and increases PVR.
59. EP low doses affect beta-receptors, and a high dose affects alpha-receptors; it is used in anaphylaxis.
60. Dopamine in low dose effects renal blood flow, medium increases HR.

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