Pharma Tips-10

71. Terbutaline and albuterol are used to treat asthma, exercise induced asthma, main side effects is tremors, anxiety, fear, restlessness, insomnia, confusion, irritability, headache, and psychotic states; dyspnoea, weakness, anorexia, nausea, and vomiting.
72. Anticancer drugs toxicity:
  • Renal toxicity: cisplatin, methotrexate (crystallization).
  • Hepatic: 6-MP, bussulfan and cyclophosphamide.
  • Cardiac: doxorubicin, daunorubicin.
  • Neurologic: vincristine, cisplatin, paclitaxel.
  • Immunosuppressant: cyclophosphamide, MTX and cytarabine.
  • Others: cyclophosphamide (hemorrhagic cystitis), procarbazine (leukemia), asparaginase (pancreatitis).
73. Hemorrhagic cystitis caused by cyclophosphamide can be prevented by using mesna that traps acrolein the metabolite of the drug, so it is protective.
74. Clozapine= clozaril; olanzapine= zyprexa, quetiapine= seroquel, risperidone= risperdal are 2nd generation antipsychotics.
75. Alcohol withdrawal treatment gives thiamine Vitamin B1 to prevent Wernicke’s encephalopathy.

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