Pharma Tips-6

51. Alpha1-receptors in the sex organs inhibit ejaculation and in the liver cause glycogenolysis.
52. Alpha2-receptors present in the pre-junctional nerve terminals decrease the release and synthesis of NE, platelet aggregation and decrease insulin secretion.
53. Beta1-receptors in the heart in the SA node increase HR (+ve inotropic effect), AV node increases conduction velocity (+ve dromotropy).
54. Beta2-receptors in the blood vessels cause vasodilation leads to decreased PVR, decreased diastolic pressure, decreased afterload, uterus relaxation, and bronchioles dilation.
55. Beta2-receptors in skeletal muscles increase glycogenolysis, leading to contractility (tremor), in liver cause glycogenolysis, in pancreas increase insulin secretion.

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