Pharma Tips-16

101. Erythromycin monotherapy is not used in COPD because of lowered activity against Haemophilus influenzae.
102. Co-administration of aminoglycosides with vancomycin or loop diuretics increases the risk of ototoxicity and nephrotoxicity and co-administration with penicillins result in aminoglycoside inactivation.
103. Telithromycin may cause fatal hepatotoxicity and it is contraindicated in myasthenia gravis.
104. SMX ∕ TMP cause SJS increases the effect of sulfonylureas and warfarin.
105. Aminoglycosides like gentamicin, tobramycin and amikacin are the treatment of choice for acute pyelonephritis.

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