116. Dexrazoxane is used as cardio-protective agent from cardiac toxicity associated with doxorubicin treatment; Mesna is an uro-protectant from hemorrhagic cystitis secondary to cyclophosphamide or ifosfamide treatment.
117. Vinca-alkaloids cause autonomic neuropathy presents with constipation and abdominal pain and stool softeners or stimulant laxatives are used; Amifostine is a cyto-protectant used to reduce xerostomia (dry mouth) in patients undergoing radiation therapy for head and neck cancer.
118. Bronchiectasis is an abnormal dilation of airways in the lungs, causing excessive mucus production.
119. Pertussis is a disease of the respiratory mucous membrane.
120. Possible teratogenic effects of some drugs:-
117. Vinca-alkaloids cause autonomic neuropathy presents with constipation and abdominal pain and stool softeners or stimulant laxatives are used; Amifostine is a cyto-protectant used to reduce xerostomia (dry mouth) in patients undergoing radiation therapy for head and neck cancer.
118. Bronchiectasis is an abnormal dilation of airways in the lungs, causing excessive mucus production.
119. Pertussis is a disease of the respiratory mucous membrane.
120. Possible teratogenic effects of some drugs:-
- Diazepam= cleft lip and palate abnormality
- Fluconazole= multiple synostosis, congenital heart defects, skeletal anomalies, and dysmorphic facial features
- Statins= CNS and limb anomalies
- Lamotrigine= isolated oral clefts
- Methimazole= scalp defects such as aplasia cutis congenital
- Paroxetine= cardiac malformations
- Penicillamine= connective tissue disorders (cutis laxa).
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