146. TCA side effects: weight gain, increase appetite, sedation, dry mouth, constipation, dizziness, drowsiness, palpitation, nausea.
TCA interactions: increase side effects 6 hrs space, grapefruit juice increase side effects, NSAIDs increase risk of bleeding, MAOIs may cause serotonin syndrome 1-2 weeks treatment free period, Antiarrhythmics such amiodarone, quinidine may risk of arrhythmia.
147. Beta-blockers side effects: headache, depression, dizziness, hallucinations, confusion, anorexia, nausea, drowsiness, weakness, abdominal pain, vomiting, muscle cramps, diarrhea, constipation, shortness of breath, heart failure, heart block, and bronchospasm are the most serious side effects.
Beta-blockers interactions: aluminum salts and antacids decrease the absorption of bb, alcohol increase dizziness and drowsiness, drugs that either affect the metabolism of bb by increase like rifampin or decrease like ketoconazole.
148. Cretinism is a hypothyroidism occurs in children with low metabolic rate, boated face with idiotic look, and protruding eye balls.
149. Myxedema is a hypothyroidism occurs mainly in adults with low metabolic rate, puffy face with dry skin, slow speech, amenorrhea, slow pulse and scanty hair.
150. Grave’s disease is a hyperthyroid condition with staring eyes, weight loss, soft skin, fast heart beat, high basal metabolic rate, sharp and anxious mind.
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