Pharma Tips-20

121. Drugs of choices in pregnancy:-

• Allergy→ chlorpheniramine, diphenhydramine, dimenhydrinate, intranasal sodium cromoglycate, beclomethasone, budesonide; loratadine.
• Anticoagulation→ heparin and LMWH, heparin 1st trimester, warfarin 2nd and 3rd trimester and heparin again at term.
• Anxiety→ BDZs.
• Asthma→ inhaled bronchodilators (salbutamol).
• Diabetes→insulin.

122. Panic disorder can be treated with SSRIs like citalopram, escitalopram, TCA such as imipramine, clomipramine, mirtazapine, MAOI phenelzine and tranylcypromine, BDZs like alprazolam, clonazepam, lorazepam and diazepam. 

123. Social anxiety disorder (social phobia) escitalopram, venlafaxine, Paroxetine, sertraline, propranolol, moclobemide.

124. Obsessive-compulsive disorder SSRIs fluoxetine, fluvoxamine, Paroxetine, sertraline, 2nd line option is clomipramine, venlafaxine, citalopram, and mirtazapine, risperidone may be used for augmentation.

125. Modafinil is a central nervous system stimulant that promotes wakefulness in the treatment of narcolepsy.