211. Drugs that may cause erectile dysfunction are beta-blockers such as atenolol, labetolol, propranolol, amiloride, indapamide, chlorthalidone, spironolactone, prazosin, hydrochlorothiazide, methyldopa, reserpine, clonidine, guanethidine, amitriptyline, amoxapine, imipramine, clomipramine, venlafaxine, bupropion, chlorpromazine, lithium, pimozide, fluphenazine, thioridazine, famotidine, acetazolamide, alcohol, carbamazepine, cimetidine, clofibrate, digoxin, methazolamide, norethindrone, phenytoin, primidone, finasteride, ketoconazole, methadone, smoking.
212. Drugs that may exacerbate BPH symptoms are amitriptyline, doxepin, nortriptyline, trimipramine, brompheniramine, chlorpheniramine, clemastine, cyproheptadine, loxapine, diphenhydramine, testosterone, fluphenazine, cyclobenzaprine, atropine, bethanechol, glycopyrrolate, hyoscine, ipratropium, procyclidine, pizotifen, selegiline.
213. Drugs that cause dry mouth isoproterenol, TCAs, clonidine, reserpine, propafenone, atropine, hyoscyamine, ipratropium, BDZs, flavoxate, oxybutynin, dicyclomine, loxapine, isotretinoin, cyclobenzaprine, loratadine, selegiline, prochloperazine.
214. Conditions that may decrease albumin level in plasma and thereby decrease the protein binding are burns, pregnancy, cystic fibrosis, chronic liver disease, chronic renal failure, trauma.
215. Hypothyroidism increases plasma albumin levels and thereby increasing protein binding of drugs.
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