Pharma Tips-33

186. Lithium excretion can be facilitated by the following drugs; IV urea, NaHCo3, acetazolamide, aminophylline; and hemodialysis.
187. Heat stroke symptoms are weakness, nausea and/or vomiting, tachycardia, hypotension, dizziness, headache, irritability, with neurological symptoms such as altered mental status, hallucinations, confusion, convulsion, and coma and core temperature above 40.5˚C; can be managed before emergency by stopping the activity immediately, rest in a cool shaded area, remove excessive clothing, rehydrate, ensure good air circulation.
188. Possible non-allergic causes of acute and chronic rhinitis are viral or bacterial infection, drug induced, hypothyroidism, pregnancy, vasomotor rhinitis, nasal tumors, choanal atresia, nasal septal deviation, enlarged adenoids and tonsils and CSF rhinorrhea.
189. Drugs associated with rhinitis are ACE Is, ASA, NSAIDs, beta-blockers, chlorpromazine, cocaine, guanethidine, methyldopa, oral contraceptives, phentolamine, prazosin, reserpine and topical decongestants.
190. Drugs that may cause ototoxicity are aminoglycosides like neomycin, kanamycin, amikacin, netilmicin, gentamicin, tobramycin, streptomycin. Antineoplastics like cisplatin, nitrogen mustard, methotrexate, vincristine, bleomycin and dactinomycin. Antiparasitics like quinine, chloroqine, ASA, NSAIDs, loop diuretics like ethacrynic acid, furosemide and bumetanide, macrolides like erythromycin, clarithromycin and azithromycin, tetracyclines like doxycycline and minocycline, vancomycin.

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