Pharma Tips-128

661. Drugs that dilate veins like nitrates.
662. Orthostatic hypotension (postural hypotension) results from venular dilatation, not arteriolar dilatation.
663. Nitrates can be used in cyanide poisoning promoting the formation of cyanide-methemoglobin complex, and this treated with thiosulfate to form thiocyanate which is less toxic.
664. Carvedilol is equivalent to dinitrate in the treatment of angina.
665. Loop diuretics increase urinary Na, Ca, Mg, K, and CL.

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