636. FEV = forced expiratory volume, FVC = forced vital capacity, PEF = peak expiratory flow.
637. Airways are narrow in the early morning (4am), and wide in the afternoon (4pm).
638. Spirometry is the definitive diagnosis of asthma.
639. Treatment of asthma:-
- Fast acting beta-agonist (FABA) + inhaled CTs( ICS)
- FABA + ICs + Leukotriene receptor antagonist(LTRA) or long-acting BA (6-11years)
- FABA + ↑dose ICS + LABA + LTRA (≥12 years)
- Theophylline in adults
- Severe asthma--> add prednisone
- Omalizumab may be added to ≥ 12 years in poorly controlled atopic asthma
640. Fluticasone + salmeterol = Advair, budesonide + formeterol = Symbicort.
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