626. Elimination half-life (t½) = 0.693*Vd/CL.
627. Drugs need about 6-7 half-lives to reach Css.
628. The nearer of the drug response curve to the Y-axis, so the drug is more potent and has a stronger affinity. The further the drug response curve from the X-axis, the more the efficacy. If the drugs are parallel, that means they work on the same receptors.
629. Codeine is a partial agonist, morphine is a full agonist if the conc. of partial agonist increases, so that leads to decrease the effect of the full agonist (antagonism).
630. Phenoxybenzamine forms an irreversible covalent bond.
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