1826. Initial dose of atropine in the treatment of sinus bradycardia may exacerbate bradycardia (typically <0.5 mg).
1827. Quinidine is a class Ⅰa antiarrhythnic agent used as a sustained-release tablet to decrease gastrointestinal side effects and to provide more even plasma levels and less frequent dosing.
1828. Low doses of aspirin and other salicylates inhibit tubular secretion of uric acid, increasing uric acid levels, leading to gout or worsening the case.
1829. Nicotinic acid reduces uric acid excretion in kidneys, increasing uric acid levels, leading to gout.
1830. Cytotoxic drugs increase nucleic acid levels that are metabolised to uric acid, increasing the risk of gouty attacks.
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