1746. Henderson-Hasselbalch equation describes the pKa and pH of a weak acid or base.
1747. The Noyes-Whitney equation describes the rate of dissolution of a solid drug.
1748. Amiodarone has a very long half-life (up to 50 days); the therapeutic effect may be delayed for weeks, and side effects may persist for up to 4 months after therapy ends.
1749. Propranolol is used to treat hyperthyroidism because it provides symptomatic relief and reduces tachycardia, sweating and tremor; it also inhibits the conversion of thyroxine (T₄) to triiodothyronine (T₃).
1750. Tenecteplase (TNKase) is easier to administer than tissue plasminogen activator (t-PA) as a single IV bolus dose for acute management of MI.
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