Pharma Tips-320

1616. Lanoxin tablets and lanoxicaps (liquid form) have the same potency; lanoxicaps are more absorbed (90-100%) and less variable than lanoxin tablets. Digoxin is recommended with diuretics, ACEIs, and BBs to treat heart failure.
1617. Hydralazine may cause systemic lupus erythematosus (SLE) in long-term therapy; CBC should be performed, and antinuclear antibody titers should be obtained. 
1618. A combination of hydralazine + isosorbide dinitrate decreases mortality in heart failure.
1619. SLE (systemic lupus erythematosus) symptoms may include fatigue, malaise, low-grade fever, joint aches, butterfly rash, chest pain, and overall pain.
1620. Beta-blockers are recommended to treat heart failure due to left ventricular dysfunction, especially HFrEFunless contraindicated for use or due to side effects like hypotension, bradycardia and bronchospasm.

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