1386. Sulfasazine decreases the gastrointestinal absorption of digoxin.
1387. Gentamycin in high doses causes nephrotoxicity and ototoxicity (reversible).
1388. Type I diabetes mellitus has beta cell destruction (insulin deficiency).
1389. Type II diabetes mellitus is characterised by insulin resistance and defects in secretion (obese).
1390. Diagnosis of diabetes mellitus:-
- Random plasma glucose ⩾ 11.1 mmol/L.
- Fasting plasma glucose (FBG) 8 hours ⩾ 7 mmol/L.
- Plasma glucose level ⩾ 11.1 mmol/L (2 hrs after 75g oral glucose).
- HbA1c ≥ 6.5% (48 mmol/mol).
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