Pharma Tips-266

1351. Endotoxin is a lipopolysaccharide in the cell wall of Gram-negative bacteria and causes intravascular coagulation.
1352. Pyrexia (fever) can be caused by penicillins. cephalosporins, vaccines, heparin, phenytoin, quinidine, carbamazepine, lamotrigine, vancomycin, methyldopa, sulfonamides.
1353. An increase in INR increases the risk of bleeding, while a decrease in INR increases the risk of clotting (coagulation).
1354. Meperidine can cause seizures.
1355. Codiene < meperidine < oxycodone < fentanyl as a pain killer, and the least potent is the most allergic.

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