686. Dopamine main side effect is psychosis.
687. Pergolide is a dopamine agonist, it is used in Parkinson's disease.
688. Parkinsonism signs and symptoms are resting tremor, bradykinesia, muscle rigidity, postural instability, flat face. It is characterized by the presence of too much acetylcholine and too little dopamine. L-dopa crosses BBB to form dopamine.
689. Chlorpromazine, haloperidol, and thioridazine lower seizure threshold, they block dopamine receptors and cause pseudo-parkinsonism, bradykinesia, rigidity, akathisia, and dystonia.
690. Muscarinic blocking drugs may cause acute dystonia.
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