Pharma Tips-194

991. Fever is a predictor of a more serious drug reaction.
992. Drug challenges are more useful than the skin test.
993. Most patients who think they are allergic to penicillin are not.
994. Risk of reacting to cephalosporins in a patient with a history of penicillin allergy is less than 1%.
995. Warfarin metabolism is inhibited by Bactrim which leads to increased INR and increased risk of bleeding.