Pharma Tips-193

986. Benzodiazepines side effects may include sedation, confusion, headache, dizziness, fatigue, amnesia, constipation, urinary retention, nausea, weight gain/loss, diplopia, chest pain, nasal congestion, dry mouth, and light-headedness. 

987. Benzodiazepines interactions; for example coffee and tea decrease sedative effect, alcohol increases the sedation effect and headache of BDZs space them by 6 hours, St. John's wort increases CNS depression.

988. NSAIDs side effects may include headache, vertigo, dizziness, nervousness, tinnitus, depression, drowsiness, insomnia, epigastric pain, nausea, and constipation.

989. NSAIDs interactions for example nephrotoxicity may be increased if given with ACEIs, cyclosporin, or diuretics, alcohol and warfarin increase the risk of bleeding, NSAIDs decrease the antihypertensive effect of some antihypertensive agents, NSAIDs decrease excretion of lithium and aminoglycosides, increase lithium concentration leads to confusion, tremor, polydipsia, and polyuria.

990. Calcium-channel blockers side effects may include headache, nausea, dizziness, drowsiness, palpitation (dihydropyridines), bradycardia (non-dihydropyridines), peripheral edema (ankle edema), fatigue, and flushing.

Pharma Tips-192

981. ACE inhibitors side effects may include a dry cough, postural hypotension or hypotension could be avoided by giving the dose at bedtime or to sit down, headache, dizziness, fatigue, hyperkalemia, nausea, angioedema. 

982. Angioedema is swelling in the face, mouth, lips, tongue or throat. 

983. ACE inhibitors interactions such as alcohol, diuretics may cause hypotension with ACEIs, NSAIDs may decrease the antihypertensive effect of ACEIs, ACEIs increase lithium levels, potassium-sparing diuretics with ACEIs may cause hyperkalemia.

984. Quinolones antibiotics side effects may include nausea, stomach upset, headache, drowsiness, dizziness, insomnia, light-headedness and vomiting.

985. Quinolones antibiotics interactions such as excessive caffeine increase nervousness, the absorption of quinolones is reduced by sucralfate, antacids containing aluminium or magnesium and also by calcium, iron, and zinc salts to avoid this take it 2 hours before or 6 hours after, quinolones  elevate levels of antidiabetic agents that may cause hypoglycemia, quinolones increase statins levels causing muscle pain, quinolones enhance the effect of warfarin (risk of bleeding).